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  • Accordingly, oral clearance normalized per body weight was higher in the younger children.
  • All patients recovered with supportive care.
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Without knowledge of the background incidence and recurrence in a Neurontin generic For Order population not treated with NEURONTIN, it is impossible to know whether the incidence seen in this cohort is or is not affected by treatment. Some of these could represent seizure-related deaths in which the seizure was not observed, e. This represents an incidence of 0. Although this rate exceeds that Neurontin generic For Order in a healthy population matched for age and sex, it is within the range of estimates for the incidence of sudden unexplained deaths in patients with epilepsy not receiving NEURONTIN ranging from 0.

Consequently, whether these figures are reassuring or raise further concern depends on comparability of the populations reported upon to the NEURONTIN cohort and the accuracy of the estimates provided.

Advise patients to discard half-tablets not used within 28 days of dividing the scored tablet. Advise patients of the need assay in Chinese hamster lung cells; it did not produce significant increases in chromosomal aberrations in the in vitro Chinese hamster lung cell assay; it was negative in the in vivo chromosomal aberration assay and in the in vivo micronucleus test in Chinese hamster bone marrow; it was Neurontin generic For Order in the in vivo mouse micronucleus assay; and it did not induce unscheduled DNA synthesis in hepatocytes from rats given gabapentin.

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